Treatment approaches for urachal cancer: Use of immunotherapy and targeted therapies

Urachal cancer is a rare genitourinary malignancy that arises from the embryologic remnant of urachus. The considered to be aggressive, with no clear consensus on appropriate management for advanced disease. Although traditionally related bladder given its origin, several next generation sequencing studies have revealed genomic profile this most closely resembles colorectal cancer. Moreover, these identified potentially actionable mutations including EGFR, KRAS and MET. In addition, recent data suggests immunotherapy may benefit some patients urachal Nonetheless, continued research warranted better understand how treat